ATI5

ATI5 - Development of a small pilot plant-system for collagen extraction

Objectives

O7 – Set up a pilot scale process to extract collagen and to produce collagen peptides from P. physalis.

The purpose of this task is to set up a pilot scale process to extract collagen and to produce collagen peptides from P. physalis. As a result of this activity, it is expected to obtain 3 deliverables: prototype production in pilot scale (30 L) of extracted collagen and collagen hydrolysate for testing and evaluation (D5.1); report based on the results from pilot production (D5.2), and recommendation for small pilot-scale set up (D5.3). The following image illustrates the process to extract collagen at pilot scale.

ATI 5.1 - Extraction of collagen and collagen peptides in pilot scale

Based on the research- and analysis results from T1.2. and T2.1. we will perform collagen extraction and enzymatic hydrolysis in pilot scale. To make sure the processes in T1.2. and T2.1. are scalable, both processes will be scaled in 30 L tanks at Nofima with equipment that is comparable to those in industrial scale at Biotep. Stepwise upscaling ensures the translation of production from laboratory to commercial scale. In this stepwise scaling, the process can be evaluated, and production issues resolved, also yield and bioactivity upon processing larger volumes (including centrifugation, filtration and drying) will be compared to that of the lab scale. We will ensure that the pilot scale production is reproducible and suited for industrial scale production of extracted collagen and collagen peptides. This task will be performed by Nofima, Uminho and UAÇ.

ATI 5.2 - Small Pilot scale set-up

Based on the results from T5.1. Nofima will be able to give advice on what type of equipment is recommended to implement in a small pilot plant-facility. This task will be performed by Nofima, Uminho and UAÇ.